Subject selection criteria, lesion site, the nature and timing of the assessment, and lack of agreement on assessment methods are all responsible for the variability in these reported rates (Stone et al., 1991 Azouvi et al., 2002). The reported incidence varies from 10 to 82% following right- and from 15 to 65% following left-hemisphere stroke (Plummer et al., 2003). Sufferers may even fail to perceive their own body parts (Mesulam, 1999). Its most typical feature is failure to report or respond to stimuli presented from the contralateral space, including visual, somatosensory, auditory, and kinesthetic sources. Unilateral neglect (UN) is a heterogeneous perceptual disorder that often follows stroke, especially after right hemisphere lesion. More rigorous studies should be done on repetitive transcranial magnetic stimulation (rTMS) before it can be concluded that it is a promising treatment for UN. PA appeared to be the most effective intervention based on the results of pooled analysis. No significant mean ES in sensitivity analysis was found for long-lasting effects across all BIT outcomes. Meta-analysis showed that for immediate effects, the BIT conventional subscore had a significant and large mean effect size (ES = 0.76 95% CI 0.28–1.23 p = 0.002) whereas the BIT total score showed a modestly significant mean ES (ES = 0.55 95% CI 0.16–0.94 p = 0.006). Prism Adaptation (PA) was the most commonly used intervention while continuous Theta-burst stimulation (cTBS) appeared to be a new approach. All had the same weakness of low power with smaller samples and limitation in the blinding of the design. Out of 201 studies initially identified, 12 RCTs covering 277 participants were selected for analysis. Randomized controlled trials (RCTs) of neglect treatment strategies for stroke patients which used the Behavioral Inattention Test (BIT) as the primary outcome measure were eligible for inclusion. A systematic review of the effectiveness of rehabilitation for persons with unilateral neglect (UN) after stroke was conducted by searching the computerized databases from 1997 through 2012.
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